In Vivo Pharmacology Expertise
With over 50 years of experience, Pharmacology Discovery Services conducts non-GLP efficacy and PK studies to meet in vivo pharmacology needs of our clients. We offer efficacy models in six major therapeutic areas incorporating biomarkers and outcome measures to enable greater prediction of success in the clinic.
Each of our Technical Directors specializes in selected therapeutic areas so they may provide expert scientific support to our clients. This involves consulting with clients to identify an appropriate model to meet their scientific objectives, designing studies, and writing the custom protocols and statements of work (SOWs) to meet quality assurance guidelines. They also work closely with our Study Directors to assure that SOWs are clear and that all methods and timelines are feasible. Our laboratory staff also averages 15 years of experience conducting in vivo pharmacology studies.
Accreditations & Certifications
- AAALAC accredited vivarium with OLAW assurance
- In compliance with European animal welfare standards
- Biosafety Level 2 Facility
Technical Capabilities
Pharmacology Discovery Services has a broad range of experience with all types of agents used in drug discovery programs to develop potential therapeutics such as small molecules, biologics, cellular agents, vaccines, RNAi, liposomal formulations, and nanoparticles.
Formulation and Dosing Options for our in vivo pharmacology models include:
- Common routes of administration: ID, ICV, IM, IP, IT, IV, PO, SC, Intra tumoral, Topical, Vaginal
- Short and Long-term Continuous IV Infusion
- Adjustable Dose Schedule – qd, bid, tid, qid
- Formulation Optimization Services
Additional services for your in vivo pharmacology study:
- Bioassay, blood gases, clinical chemistry, exposure (PK), flow cytometry, gross pathology, hematology, necropsy, surgery
Custom Model Development
Consultative development of custom models with wild type or genetically modified models
Partner Lab
Pharmacology Discovery Services is a Partner Lab of Eurofins Discovery. For >40 years, Eurofins Discovery network of companies has been a trusted CRO supporting global Drug Discovery clients from Target ID through to Candidate Selection. Eurofins Discovery was built by bringing together the market leading drug discovery expertise of Panlabs, Cerep, EMD Millipore's Discovery & Development Solutions business, and Villapharma Research to offer a comprehensive package of drug discovery products and services, including in vitro assays, cell-based phenotypic assays, safety & efficacy, ADME-Tox, chemistry and custom proteins & assay development services. This partnership grants our clients access to a broad portfolio of drug discovery products and services to help advance their drug candidates to the clinic.
