PDS >> Efficacy Models

In Vivo Efficacy Models

 

With over 30 years of experience, Pharmacology Discovery Services conducts non-GLP safety and efficacy in vivo studies to meet the in vivo pharmacology needs of our clients.  We offer efficacy models in eight different therapeutic areas that incorporate biomarkers and outcome measures to enable greater prediction of success in the clinic.  Each therapeutic area is supported by Technical Directors and Study Directors that provide expert scientific support to our clients.  This involves consulting with clients to identify an appropriate model to meet their scientific objectives, designing studies and writing the custom protocols and statements of work (SOWs) to meet quality assurance guidelines.  Also, our laboratory staff averages 15 years of experience conducting in vivo pharmacology studies.

 

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A portfolio of Anti-infective models, that includes ESKAPE pathogens.  
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Models include hypertension, thrombosis and arrhythmia.
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Models include: epilepsy, affective disorders, neuroleptic, multiple sclerosis, acute/ inflammatory/ neuropathic pain.
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Models that allow the examination of GI motility, colonic function.
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Models of immune modulation, restoration, suppression or stimulation and specific models of organ damage.
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Type I and Type II diabetes models with a broad selection of outcome measures.
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Both Xenograft and Syngeneic models and custom model development with client-specified cell lines.
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Models include pulmonary inflammation and fibrosis, antitussive suppression, bacterial pneumonia.