With over 50 years of experience, Pharmacology Discovery Services conducts non-GLP safety and efficacy in vivo studies to meet the in vivo pharmacology needs of our clients.  We offer efficacy models in specialized therapeutic areas that incorporate biomarkers and outcome measures to enable greater prediction of success in the clinic. Each therapeutic area is supported by Technical Directors and Study Directors that provide expert scientific support to our clients. This involves consulting with clients to identify an appropriate model to meet their scientific objectives, designing studies and writing the custom protocols and statements of work (SOWs) to meet quality assurance guidelines. Also, our laboratory staff averages 15 years of experience conducting in vivo pharmacology studies.

Comprehensive In vitro and In vivo antimicrobial services. Our collection has thousands of strains, many from the FDA-CDC AR-BANK 

Models for efficacy testing and side-effect profiling. Models include: Acute, Inflammatory, Neuropathic and Translational pain

Models to assess gastric acidity, irritation, ulceration and molity. Renal function and renal failure models.

Dozens of validated disease models: Arthritis, Dermatitis, Diabetes, Fibrosis, IBD, Lupus, NASH, Pruritus and Psoriasis.

Diabetes (Type I and II), NASH, obesity and pancreatitis models.

Syngeneic murine or human tumor xenograft models that include subcutaneous, orthotopic or disseminated disease models.