Antimicrobial Drug Discovery Services
To support the development of novel antimicrobials Pharmacology Discovery Services provides both in vitro and in vivo antimicrobial drug discovery services. Our in vitro microbiology services includes Minimum Inhibitory Concentration (MIC) testing with over 750 strains. Most strains are phenotyped and the acquired antibiotic resistance genes are genotyped. Over 80 validated in vivo efficacy models are also available in either thigh or lung infection models. We also provide pharmacokinetic (PK) and safety/tolerability in vivo models to enable the evaluation of compounds prior to conducting efficacy studies. All study protocols are written and reviewed by our team of highly experienced antimicrobial Technical and Study Directors and our team may also develop custom services to meet the specific needs of your drug discovery program.
Through our Partner Lab, Eurofins Pharma Discovery Services, our clients also have access to other services that include: in vitro pharmacology, in vitro ADME-Tox, and assay development services. With the breadth antimicrobial drug discovery services from Pharmacology Discovery Services and other assays provided by Eurofins Pharma Discovery Services our clients have access to thousands of assays to support their drug discovery programs.